Cryopreservation is a buzz word now not only in nepal but all over the world. Cryopreservtion has started to be adopted in many field of health. Many cases of cryopreservation has been carried in the hope of saving the life of disease patient. This is hope to give new life to the weak and diseased people.Cryopreservation has been adopted in the field of infertility and reproduction too, also called fertility preservation. Freezing technology is a breakthrough in the field of IVF. But in current condition with the current techology, cryopreservation is mainly or excessively used in fertility preservation. It is helping those couple who want to delay their pregnancy to focus
What is cryopreservation?
Cryopreservation is the process of preserving biological components such as cell, tissues, organelles, or organs by maintaining a low temperature. Liquid nitrogen or solid carbon dioxide is used to maintain the low temperature depending upon the temperature needed. Cryopreservation was first discovered by an English biologist, Ernest John Christopher Polge, in 1949 accidentally. He accidentally discovered the cryoprotective properties of glycerol on fowl sperm. He solved the mystery of preserve living cells and tissues by maintaining a very low temperatures. Fertility preservation is a process of saving or protecting egg, sperm or embryo so that it can be used directly later to produce biological children.
Cryopreservation for male
Cryopreservation is sometime very essential while going before chemotherapy, radical surgery or operation related to reproductive system. Sperm Cryopreservation gives option to freeze their sperm and store, until pregnancy is desired. Sperm cryopreservation is quick and non-invasive.
Cryopreservation for women
The fertility health degrades with age. Fertility is ageist. Fertility healthy start decreasing gradually at about age 32. The fertility of the women rapidly decline from age 35. By the age of 40, the potential of bearing child will be half. The chances of conceiving at 40 will be around 5%, whihch is 4 time less than the age of 30. Those women who want to persue their career yet want to have a healthy child and don't want to compromise the quality of egg, can preserve their egg. These preserved egg can be used later after they achieved their goal and when feel like having a child.
Reason for fertility preservation
Fertility preservation is done generally to address the problems such as:
Cancer or other medical reason: If the patient is going through the chemotherapy for cancer or other diagnosis that require chemo, then it is best to preserve the sperm or egg before the procedure.
Focus on Career: In today's world, there is more competition. If you are that one type who focus on their career, yet don't want to compromise the quality and quantity of your child health. It is best to do what is right for them.
Deteriorating quality and quantity of sperm or egg: Due to the health hazard, and the life style we have adopted, the production and quality of the sperm and egg are compromised along with our overall health. Sperm count are getting lower and lower due to the pollution and other factor such as lack of exercise, unhealthy fooding, use of chemicals, etc.
Cancer or other medical reason: If you are going through the chemo-therapy or radiation for cancer, it is always advicable to store your sperm or egg. A body may malfunction and disrupt hormone production. A studies show that chemotherapy during puberty, can damage testicles and affect the ability to produce sperm. Chemotherapy kills cell that are dividing quickly. Since sperm cells divide quickly it could be a easy target.
High risk occupation: If you work on a chemical factory and is constantly on the field that have chances of harmful UV ray exposure, it is always best to keep your sperm or egg safe.
Step involved in cryopreservation
Cryopreservation (fertility preservation) involves diagnosing for the egg, extraction, freezing and storing the egg for preferable time in women. The cryopreservation process for male involves diagnosis for disease, sperm extraction, quality and quantity analysis of sperm and, freezing and storing.
Risk involved in cryopreservation
Cryopreservation is recommended to be done in a trusted organization. Damage to the cells (egg or sperm) is done during freezing stage of cryopreservation. The damage is done mainly due to solution effects, extracellular ice formation, dehydration, intracellular ice formation or due to human error or ignorance. These damage may result in defected birth or miscarriage.